National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Oral carriage of Candida species is common in HIV infected patients. Oral sputum was taken from study group of 75 patients and control group of 26 patients. Samples were cultured on 1% G.A. sabouraud dextrose agar to isolate candida species. Out of total 75 HIV positive asymptomatic patients, Male : Female ratio was 4:1.7. Candida species C.albicans, C.tropicalis, C. pseudotropicalis, C.krusei, C.glabrata, C.parapsilosis, C.guilliermondii were identified. Oral candida carriage rate among study group were 65.33% where as in control group it was 42.31%. In study group C.albicans was 69.39% followed by other non albicans species. In control group also C.albicans was the predominant species (36.36%) followed by other non albicans species. In study group sensitivity of C. albicans to nystatin was 97.06% followed by amphotericin-B 91.17%, clotrimazole 88.24%, fluconazole 82.36%, ketoconazole 76.47%, and itraconazole 73.53%. Sensitivity of control group to nystatin was 100% followed by amphotericin-B 100%, clotrimazole 75%, fluconazole 50%, ketoconazole 25%, and resistant to itraconazole. Out of study group 38 patients had CD4+ cell count 200-499 Cells/μL, of whom 26 were oral Candida carrier. There were significant fungal associations with gender, age and antiretroviral therapy (P≤0.05).
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