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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(11): 542-545
DOI: http://dx.doi.org/10.20546/ijcmas.2016.511.064


Prevalence of Oral Candida Carriage Rate among HIV Infected Asymptomatic and Non Infected Persons, their Antimycotic Sensitivity and its Association with CD4 Counts
Smita Kulshreshtha1*, Usha Verma1, P.K. Khatri1 and Prameshwar Lal2
1Department of Microbiology, Dr. S. N. Medical College, Jodhpur, Rajasthan, India
2C.H.C. Lohawat, Jodhpur, Rajasthan 342003, India
*Corresponding author
Abstract:

Oral carriage of Candida species is common in HIV infected patients. Oral sputum was taken from study group of 75 patients and control group of 26 patients. Samples were cultured on 1% G.A. sabouraud dextrose agar to isolate candida species. Out of total 75 HIV positive asymptomatic patients, Male : Female ratio was 4:1.7. Candida species C.albicans, C.tropicalis, C. pseudotropicalis, C.krusei, C.glabrata, C.parapsilosis, C.guilliermondii were identified. Oral candida carriage rate among study group were 65.33% where as in control group it was 42.31%. In study group C.albicans was 69.39% followed by other non albicans species. In control group also C.albicans was the predominant species (36.36%) followed by other non albicans species. In study group sensitivity of C. albicans to nystatin was 97.06% followed by amphotericin-B 91.17%, clotrimazole 88.24%, fluconazole 82.36%, ketoconazole 76.47%, and   itraconazole 73.53%. Sensitivity of control group to nystatin was 100% followed by amphotericin-B 100%, clotrimazole 75%, fluconazole 50%, ketoconazole 25%, and resistant to itraconazole. Out of study group 38 patients had CD4+ cell count 200-499 Cells/μL, of whom 26 were oral Candida carrier. There were significant fungal associations with gender, age and antiretroviral therapy (P≤0.05).


Keywords: Candida, HIV, CD4, Oropharyngeal Candidiasis, Oral candida carriage, Fluconazole , ART.
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How to cite this article:

Smita Kulshreshtha, Usha Verma, P.K. Khatri and Prameshwar Lal. 2016. Prevalence of Oral Candida Carriage Rate among HIV Infected Asymptomatic and Non Infected Persons, their Antimycotic Sensitivity and its Association with CD4 CountsInt.J.Curr.Microbiol.App.Sci. 5(11): 542-545. doi: http://dx.doi.org/10.20546/ijcmas.2016.511.064