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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(12): 1515-1522
DOI: https://doi.org/10.20546/ijcmas.2018.712.179


Bacteriological Study of Neonatal Septicemia and their Antibiotic Susceptibility Patterns at MGM Hospital, Warangal
Ravindar Sirikonda and Kondal Rao Ravilla*
Department of Microbiology, Kakatiya Medical College, Warangal, Telangana, India
*Corresponding author
Abstract:

Neonatal septicemia is still a leading cause of mortality and morbidity in developing countries like India. This prospective study involved 382 clinically suspected cases of neonatal septicemia over a period of one year from April 2014 to March 2015. Of the total 382 cases studied 174 (45.54%) were blood culture positive. Among the culture positive cases, septicemia was more common in male neonates, seen in 55.23%, compared to 44.76% of female neonates. Of the 174 culture positive cases, early onset septicemia (EOS) was more common, seen in 75.86% compared to late onset septicemia (LOS) in 24.14% of the cases. Gram negative organisms were the predominant causative agents of septicemia in(61.49%), compared to Gram positive organisms in (38.50%) of the cases. Klebsiella pneumoniae was the commonest gram negative isolate in 39.65% of cases, followed by Staphylococcus aureus in 22.41% of cases. All the Gram positive isolates were 100% susceptible to Vancomycin followed by Amikacin 94.87% , linezolid 89.74% and 100% resistant to Penicillin . Majority of Gram negative isolates were susceptible to Meropenem followed by Amikacin and ciprofloxacin, while maximum resistance was noted with Ampicillin, followed by Cefuroxime, Cefotaxime, Ceftazidime and Gentamicin . To conclude, Blood culture is still the “Gold standard” for the diagnosis of septicemia in neonates and should be done in all cases of suspected septicemia prior to starting the antibiotics.


Keywords: Blood culture, Neonatal septicemia, Klebsiella pneumoniae, Staphylococcus aureus
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How to cite this article:

Ravindar Sirikonda and Kondal Rao Ravilla. 2018. Bacteriological Study of Neonatal Septicemia and their Antibiotic Susceptibility Patterns at MGM Hospital, Warangal.Int.J.Curr.Microbiol.App.Sci. 7(12): 1515-1522. doi: https://doi.org/10.20546/ijcmas.2018.712.179