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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2018) [Effective from January 1, 2018]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here
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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(11): 3264-3268
DOI: https://doi.org/10.20546/ijcmas.2018.711.376


Bacteriological Profile and Antibiotic Sensitivity Pattern of Neonatal Sepsis in a Tertiary Care Hospital
Pavneet Kaur and Sarbjeet Sharma
Department of Microbiology, Sri Guru Ram Das Institute of Medical Sciences & Research, Amritsar, India
*Corresponding author
Abstract:

India accounts for 30% of neonatal deaths globally. Bacterial sepsis is a significant cause of morbidity and mortality in newborns. The study helps to make antibiotic policy in neonatal sepsis. The main objective is to study the incidence of multidrug resistant gram negative and gram positive organisms causing neonatal septicemia and their antibiotic sensitivity pattern. The study was conducted in the Department of Microbiology over a period of one year. Sample of blood was collected under aseptic precautions and processed by standard techniques. Microorganisms were identified by Gram staining, standard biochemical tests and appropriate antibiograms. The common microorganisms responsible for neonatal sepsis were identified, and the resistant strains were studied. After identification and antibiotic susceptibility testing, beta-lactamases were detected as per CLSI guidelines. In 233 blood cultures 18.9 % (44/233) culture positivity was seen. Out of them, 31 (70.5%) were Gram negative and 13(29.5%) were Gram positive. Klebsiella pneumoniae subspecies pneumoniae (45.5%) was the most common isolate. ESBL producers were maximum (54.8%.) 25.8% of the isolates were positive for AmpC production. The diverse microbiological pattern of neonatal septicaemia demands the need for review of neonatal sepsis. The evaluation of the pathogens and their antibiotic susceptibility is a relevant guide in the antibiotic therapy.


Keywords: Neonate, Blood culture, ESBL, AmpC, GNB
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How to cite this article:

Pavneet Kaur and Sarbjeet Sharma. 2018. Bacteriological Profile and Antibiotic Sensitivity Pattern of Neonatal Sepsis in a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 7(11): 3264-3268. doi: https://doi.org/10.20546/ijcmas.2018.711.376