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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(11): 3130-3137
DOI: https://doi.org/10.20546/ijcmas.2018.711.359


Evaluation of Propofol and Ketofol Anaesthesia Following Atropine, Diazepam and Fentanyl Premedication in Dogs
P. Thejasree, P. Veena*, N. Dhanalakshmi and K. Veerabrahmaiah
Department of Veterinary Surgery and Radiology, College of Veterinary Science, Tirupati (A.P.), India
*Corresponding author
Abstract:

Twelve dogs of either sex presented to the college clinic with surgical conditions like pyometra, urethral calculi, fractures and mammary tumours were utilized to study the effect of ketofol and propofol after premedication with atropine sulphate, diazepam and fentanyl. The animals were divided into two groups of six animals each. Ketofol (1:1) combination was given intravenously in group I dogs. Propofol @ 6 mg/kg b.wt. intravenously was given in group II dogs. Induction quality was excellent, smooth and attained sternal recumbency rapidly without struggling in all animals in both groups. Recovery from anaesthesia was smooth and excitement free in both groups. However, slightly prolonged recovery was a consistent observation in propofol group. No significant difference was noticed in RT, RR, PR and SpO2 values between the groups. Non-significant increase in HR was recorded in group I dogs. A significant decrease in HR was observed in dogs subjected to propofol anaesthesia. ECG studies did not reveal any abnormality except increase in amplitude of QRS complex duration in both groups. The haematological parameters like Hb, PCV were differed significantly within the group and between the groups. However, all the fluctuations were within the normal physiological range. Changes in biochemical parameters like AST, ALT and ALP were significant between the groups and were within the normal physiological range in both groups. Ketofol with atropine, diazepam and fentanyl premedication provided better surgical anaesthesia with smooth induction and rapid, safe and smooth recovery in dogs.


Keywords: Propofol and Ketofol, Anaesthesia, Atropine, Diazepam and Fentanyl Premedication
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How to cite this article:

Thejasree, P., P. Veena, N. Dhanalakshmi and Veerabrahmaiah, K. 2018. Evaluation of Propofol and Ketofol Anaesthesia Following Atropine, Diazepam and Fentanyl Premedication in Dogs.Int.J.Curr.Microbiol.App.Sci. 7(11): 3130-3137. doi: https://doi.org/10.20546/ijcmas.2018.711.359