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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2018) [Effective from January 1, 2018]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here
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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(11): 2878-2895
DOI: https://doi.org/10.20546/ijcmas.2018.711.331


Vaccination against Haemonchus contortus in Small Ruminants: A Review
Ishfaq Maqbool1*, Bilal Ahmad Malla2, Aquil Mohmad3, Nishchal Dutta4, Nasir Manzoor5, Bhawana Kushwaha6, Vijesh Kumar Saini7 and Irshad Ahmad Para8
1Department of Veterinary Parasitology
4Department of Veterinary Pathology, College of Veterinary Science Guru Angad Dev Veterinary and Animal Sciences University,
Ludhiana-141004, Punjab, India
5Department of Veterinary Pharmacology and Toxicology, Shere-Kashmir University of Agricultural Sciences and Technology, R S Pura- 181102, Jammu, India
2Division of Veterinary Public Health, 3Division of Veterinary Parasitology
6Division of Veterinary Parasitology, 8Division of Physiology and Climatology,
Indian Veterinary Research Institute, Izatnagar, Bareilly-243122, UP, India
7Veterinary Surgeon, Department of Animal Husbandry, Paliwal-121107, Haryana, India
*Corresponding author
Abstract:

Haemonchus contortus is one of the most important nematode species responsible for huge economic losses to small-ruminant farming in India and world over. Control is primarily based on use of anthelmintics. Over reliance on and non-judicious use of anthelmintics has lead to development of anthelmintic resistance. This wide spread anthelmintic resistance has forced to look for alternate control measures. Vaccination can significantly protect livestock against and lower the economic losses incurred due to H. contortus. Different antigens have been tried with variable success. Use of recombinant antigens has not yielded desirable protection levels. Native antigens have given significant protection but has been considered non feasible. Recent discovery that the dose as low as 5 µg of native antigen can be protective has raised hopes of developing economically feasible vaccines. Barbervax, sub-unit vaccine derived from native gut integral glycoprotein is now commercially available.


Keywords: Haemonchus contortus, Vaccine, Native antigen, Recombinant antigen, Barbervax
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How to cite this article:

Ishfaq Maqbool, Bilal Ahmad Malla, Aquil Mohmad, Nishchal Dutta, Nasir Manzoor, Bhawana Kushwaha, Vijesh Kumar Saini and Irshad Ahmad Para. 2018. Vaccination against Haemonchus contortus in Small Ruminants: A Review.Int.J.Curr.Microbiol.App.Sci. 7(11): 2878-2895. doi: https://doi.org/10.20546/ijcmas.2018.711.331