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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(11): 284-298
DOI: http://dx.doi.org/10.20546/ijcmas.2016.511.031


Antimicrobial Activity of Caralluma quadrangula (Forssk) N.E. Br Latex from Al-Shafa Taif, Kingdom of Saudi Arabia
Abd-ElAziem Farouk1,2*, N. Thoufeek Ahamed1, Othman AlZahrani1, Khalid H. Alamer3, Yassin Al-Sodany3 and Abdul Aziz Bahobail3
1Molecular Biotechnology Research Unit, Department of Biotechnology, Faculty of Science, Taif University, Al-Hawiya 888, Kingdom of Saudi Arabia
2Tsuno GmbH, Wibiloweg 16, 69123 Heidelberg, Germany
  3Department of Biology, Faculty of Science, Taif University, Al-Hawiya 888,Kingdom   of Saudi Arabia
*Corresponding author
Abstract:

Caralluma quadrangula (Forssk) N.E. Br belongs to the Asclepiadaceae family and was collected from the Al-Shafa Mountain in Taif, a city in the Mecca Province of Saudi Arabia at an elevation of 1,879 m (6,165 ft) on the slopes of the Sarawat Mountains. The plant’s latex was extracted and dissolved into five different aqueous solutions with the solvents: distilled water, Zamzam water, acetone, ethyl alcohol and Tris-HCl to yield five different extracts. The objectives of this research is to extract Caralluma quadrangula  latex using different aqueous solutions / solvents and to evaluate the inhibition zones using 5 pathogenic and non pathogenic microorganisms using six various concentrations of Caralluma quadrangula  latex. This study on Caralluma quadrangula (Forssk) N.E. Br, obtained from Al- Shafa, Taif. The research was conducted at the Department of Biotechnology, Taif University.   The bacterial strains from ATCC and the nutrient Hiveg- Agar from Himedia were utilized for the study. The antimicrobial activity was tested against both Fungi, Gram-positive and Gram-negative bacteria using the agar diffusion method. Antimicrobial activities were observed, especially against Micrococcus luteus, Candida albicans, Escherichia coli, and Pseudomonas aeruginosa strains. The higher activity was exhibited in the acetonic and ethyl alcohol extract solutions of Caralluma quadrangula latex depending upon various concentrations towards the particular organism.  These results are encouraging due to the fact that the plants are rich in antimicrobial sources that should be considered; especially antimicrobial peptides from latex extracted in Zamzam water and compounds were extracted from latex in solvent, further studies should be carried out to confirm the purification of the antimicrobial compounds.


Keywords: Antimicrobial activity, Asclepiadaceae, Caralluma, Caralluma quadrangula, latex.
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How to cite this article:

Abd-ElAziem Farouk, N. Thoufeek Ahamed, Othman AlZahrani, Khalid H. Alamer, Yassin Al-Sodany and Abdul Aziz Bahobail. 2016. Antimicrobial Activity of Caralluma quadrangula (Forssk) N.E. Br Latex from Al-Shafa Taif, Kingdom of Saudi Arabia.Int.J.Curr.Microbiol.App.Sci. 5(11): 284-298. doi: http://dx.doi.org/10.20546/ijcmas.2016.511.031