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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here
journals IJCMAS
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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(11): 2732-2737
DOI: https://doi.org/10.20546/ijcmas.2018.711.313


Study of Haematological Parameters in Pre and Post-Treated Dogs with Chemotherapy by Doxorubicin and Vincristine in Canine Transmissible Venereal Tumour
Anup Yadav1, Praveen Kumar2*, N.S. Bugalia1, Umed Singh Mehra1, Rajendra Yadav3 and Pankaj Kumar4
1Department of Veterinary Gynaecology and Obstetrics
2Department of Veterinary Medicine (LUVAS, Hisar), Haryana, India
3RVDEC, Mahendergarh (LUVAS, Hisar), Haryana, India
4Disease Investigation Laboratory, Rohtak (LUVAS, Hisar), Haryana, India
*Corresponding author
Abstract:

The present study was carried out in twenty-four dogs irrespective of age, breed, sex affected with canine transmissible venereal tumour (TVT). Affected dogs were divided equally into three groups viz. vincristine therapy (Group I) with 7 day cycle and doxorubicin therapy consisting two groups i.e. Group II with 14 day cycle and group III with 21 day cycle. Pre treatment blood sample collection was done before administration of drug i.e. Day 0, 7, 14 in Group I, Day 0, 14, 28 in Group II and Day 0, 21, 42 in Group III. Hematological parameters viz. Haemoglobin, Total erythrocytes count (TEC) and Total luecocyte count (TLC) was undertaken for study. Non-significant but declining trend of Hb concentration, leucopenia and reduction in total erythrocytes count was observed post treatment in Doxorobucin and vincristine chemotherapy.


Keywords: Doxorubicin, Vincristine, Transmissible venereal tumour
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How to cite this article:

Anup Yadav, Praveen Kumar, N.S. Bugalia, Umed Singh Mehra, Rajendra Yadav and Pankaj Kumar. 2018. Study of Haematological Parameters in Pre and Post-Treated Dogs with Chemotherapy by Doxorubicin and Vincristine in Canine Transmissible Venereal Tumour.Int.J.Curr.Microbiol.App.Sci. 7(11): 2732-2737. doi: https://doi.org/10.20546/ijcmas.2018.711.313