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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(11): 19-24
DOI: https://doi.org/10.20546/ijcmas.2018.711.003


Pathomorphological Changes in Type-2 Diabetes in Rat Model
J.K. Raval*, M.C. Prasad, H.C. Parmar, J.M. Patel, P.D. Vihol and J.H. Patel
Department of Veterinary Pathology, Vanbandhu College of Veterinary Science and A.H, Navsari Agricultural University – Navsari-396450, Gujarat, India
*Corresponding author
Abstract:

The present study was aimed for studying gross and histopathological changes in various organs of STZ-NAD induced Type –II diabetic rat model. In diabetic group rats, the gross changes included congestion in liver, kidneys, heart and brain, atrophic changes in liver, heart, pancreas, spleen, thymus, testes and epididymes, edematous mesenteric lymph nodes and ulcerations in gastrointestinal tract in comparison to control group. The histopathological changes consisted of reduction in number /size / cellular components of islets of Langerhans and necrotic /degenerative changes in pancreas while coagulative necrosis, tubular mineralization and vacuolar degeneration in kidneys.


Keywords: Type-II diabetes, Rats, Gross and histopathological changes, Kidney, Pancreas
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How to cite this article:

Raval, J.K., M.C. Prasad, H.C. Parmar, J.M. Patel, P.D. Vihol and Patel, J.H. 2018. Pathomorphological Changes in Type-2 Diabetes in Rat Model.Int.J.Curr.Microbiol.App.Sci. 7(11): 19-24. doi: https://doi.org/10.20546/ijcmas.2018.711.003