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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(10): 1261-1268
DOI: https://doi.org/10.20546/ijcmas.2018.710.141


Inducible Clindamycin Resistant Strains of Staphylococcus aureus - Associated Skin and Soft Tissue Infection
Harish Ghogare1 and Sunil Hatkar2*
1Department of Microbiology, MGM Medical College, Aurangabad, India
2Department of Microbiology, SMBT Medical College, Nashik, India
*Corresponding author
Abstract:

Staphylococcus aureus causes skin and soft tissue infections (SSTIs), if not treated with proper antimicrobials can leads to serious form of infection. Multi-drug resistant strains left us very few therapeutic alternatives, in such cases clindamycin can be a good option with true sensitivity. The clinical samples exhibiting skin and soft tissue infection received in the department of microbiology further subjected to isolation of Staphylococcus aureus. Isolated strains further subjected to D-test to detect inducible clindamycin resistant strains as per standard guidelines. Antimicrobial susceptibility testing performed for all the isolates as per CLSI guidelines. A total of 176 Staphylococcus aureus, 82 were isolated from skin and soft tissue infection. Out of 82 strains, 23(28%) were inducible clindamycin resistant strains of Staphylococcus aureus, 49(59.8%) were constitutive resistant, and 10(12.2%) were MS phenotype. All the isolates were sensitive to vancomycin, followed by doxycyclin 62(75.6%), Amikacin 60(73.2%) and 57(69.5%) were sensitive to linezolid. Detection of inducible clindamycin resistant strains of Staphylococcus aureus on routine basis is crucial for judicial use of the drug and proper institution of the therapy especially in skin and soft tissue infections.


Keywords: Staphylococcus aureus, SSTIs, AST
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How to cite this article:

Harish Ghogare and Sunil Hatkar. 2018. Inducible Clindamycin Resistant Strains of Staphylococcus aureus - Associated Skin and Soft Tissue Infection.Int.J.Curr.Microbiol.App.Sci. 7(10): 1261-1268. doi: https://doi.org/10.20546/ijcmas.2018.710.141