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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(10): 997-1009
DOI: https://doi.org/10.20546/ijcmas.2018.710.111


Antifungal Susceptibility Profile of Candida Isolates from Bloodstream Infections in Hospitalised Patients at Tertiary Care Hospital
Pallavi S. Tatte* and Pramod R. Bhise
Department of Microbiology, Dr. Panjabrao Deshmukh Memorial Medical College, Amravati, Maharashtra, India
*Corresponding author
Abstract:

During recent decades, there has been a change in the epidemiology of Candida infections, characterized by progressive shift from predominance of Candida albicans to non albicans Candida. The aim of present study to isolate and identify the different Candida spp. from BSIs and evaluate its antifungal susceptibility pattern the present study was conducted in department of Microbiology for a period of one year (January - December 2016) which included, 48 Candida spp. isolated from BSIs. The speciation was done by conventional methods. Antifungal susceptibility testing of the isolates was performed by Minimum Inhibitory Concentration test. A total of 48 isolates of Candida species were recovered from blood samples of 454 patients [Candida albicans (31.25%), C. tropicalis (25%), C. glabrata (20.84%), C. krusei (16.66%), C. parapsilosis (4.17%), C. guilliermondii (2.08%)]. Isolation of NAC spp. was significantly higher than Candida albicans. Fluconazole and Amphotericin B resistance was seen in 18 (37.5 %) and 3(6.25%) of the isolates respectively. Candidemia is emerging as a significant problem in hospitalized patients. Non albicans candida is major cause of candidemia as found in our study.


Keywords: Candida albicans, Non albicans Candida, Candidemia, Antifungal susceptibility
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How to cite this article:

Pallavi S. Tatte and Pramod R. Bhise. 2018. Antifungal Susceptibility Profile of Candida Isolates from Bloodstream Infections in Hospitalised Patients at Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 7(10): 997-1009. doi: https://doi.org/10.20546/ijcmas.2018.710.111