<records>
<record>
<language>eng</language>
<publisher>Excellent Publishers</publisher>
<journalTitle>
International Journal of Current Microbiology and Applied Sciences (IJCMAS) CODEN(USA)-IJCMO9
</journalTitle>
<issn>2319-7692</issn>
<eissn>2319-7706</eissn>
<publicationDate>2015-01-10</publicationDate>
<volume>5</volume>
<issue>1</issue>
<startPage>424</startPage>
<endPage>429</endPage>
<documentType>article</documentType>
<title language="eng">
A Regulatory/ Signaling Molecule of Group A Streptococci (GAS) May be
Responsible for Modulation of Bacterial Virulence
 </title>

<authors>
<author>
<name>Bindu Arora</name>
<affiliationId>1</affiliationId>
</author>
<author>
<name> Anupama Rao </name>
<affiliationId>2</affiliationId>
</author>
<author>
<name> Chinmaya Kashikar</name>
<affiliationId>3</affiliationId>
</author>
</authors>

<affiliationsList>
<affiliationName affiliationId="1">
Department of Biotechnology, Abasaheb Garware College, Karve Road, Pune-411 004, India
</affiliationName>

</affiliationsList>

<abstract language="eng">
<p>
Pathogenic microbes secrete various enzymes to facilitate their survival within the
host which may have direct/ indirect role to play in bacterial virulence. In the
present work, extracellular amylase producing bacteria were isolated from air, water and soil samples by serial dilution and plating method. Twenty three
bacterial isolates obtained were screened for amylolytic activity, out of which only
5 isolates showed amylolytic activity viz: Streptococcus sp., Staphylococcus sp., two Bacillus sp. and Veillonella sp., which were identified by phenotypic
characterization. The results revealed that Streptococcus sp. exhibit beta
haemolysis on blood agar and had the potential to produce 120 EU extracellular
amylase after 48 hours. This is reported here for the first time for production of
extracellular amylase. This enzyme might be a regulatory/ signaling molecule and
thus be an attractive drug target in the treatment of bacterial infections.
</p>
</abstract>
<fullTextUrl format="pdf">
http://www.ijcmas.com/vol-5-1/Bindu%20Arora,%20et%20al.pdf
</fullTextUrl>
<keywords language="eng">
<keyword> Extracellular
amylase
</keyword>
</keywords>
<keywords language="eng">
<keyword>    Group
A Streptococci
</keyword>
</keywords>
<keywords language="eng">
<keyword>Beta haemolysis</keyword>
</keywords>

</record>
</records>