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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2017) [Effective from January 1, 2017]For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2015: 85.95
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95
For more details click here
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
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Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(4): 2328-2337
DOI: https://doi.org/10.20546/ijcmas.2017.604.271


Effect of Fenugreek Seed and Leaves on Some Hematological and Biochemical Parameters in CCl4-induced Liver Injury
Firdaws A. AL-Mashhadani*
Food technology Dep., Agriculture College, Salahaddin University, Erbil, Iraq
*Corresponding author
Abstract:

This study was carried out to evaluate the effect of fenugreek plant on CCL4 –induced liver injury by following the hematological and biochemical parameters. To achieve this purpose forty male albino rats were used and divided to four groups. The first group represented control group which received normal diet and intraperitoneal injection with oil (0.5ml/kg). The second group represented the CCL (1ml/kg) model. The third group received 200 mg/kg fenugreek leaves extract by gavage. The forth group received 500 mg/kg fenugreek seed extract by gavage. The fenugreek seed and leave extracts treated group showed significant differences in AST, ALT, ALP, direct bilirubin, MDA, GSH, liver SOD, WBC, LYM and PLT when compared to CCl4 treated rats. These results indicate that these plants can be used as a good source of antioxidant and hepatic protective activities as well as a good antibiotic agent against some pathogenic bacteria. The methanolic extract of fenugreek seeds with different concentrations in ml inhibited the growth of the pathogenic E. coli, Staphylococcus aureus and Bacillus subtilis bacteria more than the aqueous extract for the fenugreek leaves and seeds.


Keywords: Fenugreek,CCL4 – Induced liver injury
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How to cite this article:

Firdaws A. AL-Mashhadani. 2017. Effect of Fenugreek Seed and Leaves on Some Hematological and Biochemical Parameters in CCl4-induced Liver InjuryInt.J.Curr.Microbiol.App.Sci. 6(4): 2328-2337. doi: https://doi.org/10.20546/ijcmas.2017.604.271