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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 6, Issue:1, January, 2017

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(1): 550-562
DOI: http://dx.doi.org/10.20546/ijcmas.2017.601.068


Anti-inflammatory Effects of Chrysactinia mexicana Gray Extract in Growing Chicks (Gallus gallusdomesticus) Challenged with LPS and PHA

J.C. Garcia-Lopez1, G. Alvarez-Fuentes1, J.M. Pinos-Rodriguez2, Y. Jasso-Pineda1, H.I. Contreras-Trevino1, M.A. Camacho-Escobar3, S. Lopez-Aguirre1, H.A. Lee-Rangel4 and J.A. Rendon-Huerta5

1Instituto de Investigación de Zonas Desérticas. Universidad Autónoma de San Luis Potosí. S.L.P. 78377. México
2Centro de Biociencias. Universidad Autónoma de San Luis Potosí. S. L. P. 78321. México 3Instituto de Industrias. Universidad del Mar Campus Puerto Escondido. Puerto Escondido Oaxaca. 71980. México
4Faculatd de Agronomía y Veterinaria. Universidad Autónoma de SanLuis Potosí. S. L. P. 78321. México
5Coordinación Académica Región Altiplano Oeste.Universidad Autónoma de San Luis Potosí.S.L.P. 78600. México
*Corresponding author
Abstract:

The effect of Chrysactinia mexicana extract on broilers challenged with LPS and PHA was evaluated. A two 2x2 factorial treatments examined effects of C. mexicana on broilers’ immune response. 200 day old Cobb chicks were assigned to the following treatments: T1 control; T2 control plus LPS or PHA; T3 control plus C. mexicana; T4 control plus C. mexicana plus LPS or PHA. For the LPS challenge; nitrites concentration, leukocyte and erythrocyte count were measured. Phytohemagglutinin (PHA) was injected into the wing web and thickness and leukocyte populations were measured at 3, 6, 12,24 and 48 h.Weight gain, feed intake and feed conversion ratio was measured. The liver, bursa, thymus, and spleen were weighted. T3 had higher (P<0.05) average daily gain, total weight gain; lower (P<0.05) feed intake and feed conversion ratio. Treatment 3 and T4 had better-feed conversion ratio compared with T1 and T2. There were differences (P<0.05) for thymus, bursa and spleen weights among treatments, with higher (P<0.05)weights for LPS treatments. For the blood cells T2 had the highest (P<0.05) counts of leukocyte and erythrocytes. Treatment with LPS and without C. mexicana had higher levels of nitrites (P>0.05). PHA increased wing web thickness at 3, 6, 12, 24 and 48 h post injection. The percentage of eosinophils in the wing web were smaller at 3,12,24 and 48 h post-PHA injection for treatment with C. mexicana. C. mexicana extract could be a possible alternative to antibiotic growth promoters in broilers.


Keywords: Chrysactinia mexicana, inflammation, broiler.

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How to cite this article:

García-López, J.C., G. Álvarez-Fuentes, J.M. Pinos-Rodríguez, Y. Jasso-Pineda, H.I. Contreras-Treviño, M.A. Camacho-Escobar, S. López-Aguirre, H.A. Lee-Rangel and Rendón-Huerta, J.A. 2017. Anti-inflammatory Effects of Chrysactinia mexicana Gray Extract in Growing Chicks (Gallus gallusdomesticus) Challenged with LPS and PHA.Int.J.Curr.Microbiol.App.Sci. 6(1): 550-562. doi: http://dx.doi.org/10.20546/ijcmas.2017.601.068
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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